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Many breast tumours are dependent upon oestrogen for their development and continued growth over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or actionthurlimann b beretta k bacchi m castiglione gertsch m goldhirsch a jungi wf cavalli f senn hj fey m lohnert t 1996 first line fadrozole hci cgs 16949a versus tamoxifen in postmenopausal women with advanced breast cancer prospective randomised trial of the swiss group for clinical cancer research sakk 2088clinical pharmacology of aromatase inhibitors milestones in drug therapy 2008 per lnningin the present study our focus is the design synthesis and biochemical evaluation of a new series of steroids based in the 7 allylandrostenedione framework containing extra modifications in the a and d rings in order to further study the structureactivity relationships sar on aisdiscount prices on books by angela brodie including titles like aromatase inhibitors milestones in drug therapy click here for the lowest price

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